Spermidine is a type of organic compound called a polyamine. It’s found naturally in foods like wheat and soybeans. As we age, polyamine levels decrease. Multiple health concerns are associated with lower levels of polyamines, but spermidine intake has been linked to delayed aging, a lower risk of death from all causes, and cognitive improvements in older adults at risk for dementia.
Proven Benefits
- Spermidine supplementation has been linked to increased lifespan and improved health span by promoting autophagy, a cellular renewal process.
- Studies suggest spermidine may help improve memory and cognitive performance, potentially offering protection against neurodegenerative diseases like Alzheimer's.
- Spermidine intake has been associated with reduced blood pressure and improved heart function. It may also enhance immune function and reduce inflammation. It may also enhance immune function and reduce inflammation.
Efficacy Studies
- Spermidine delays aging in humans
Results
Spermidine may exert specific effects on multiple organ systems engaged in cardiovascular function, anticancer immune surveillance, and neurodegeneration, thereby reducing the incidence of major age-related diseases.
Source:
Madeo et al. (2018)
Conflicts of interest
All authors are the scientific founders of Samsara Therapeutics. Didac Carmona-Gutierrez and Frank Madeo have equity interest in The Longevity Labs.
2. Higher spermidine intake is linked to lower mortality: a prospective population-based study
Results
All-cause mortality decreased with increased spermidine intake when adjusted for age, sex, and lifestyle factors. Subjects enrolled in the study in 1990 at ages ranging from 45 - 84. They were re-evaluated every 5 years through 2015. Those with the highest levels of spermidine in their diet saw the best health outcomes.
Source:
Kiechl et al. (2018)
3. The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial
Results
Subjects were given nutritional spermidine or a placebo over the course of three months in a double-blind trial. Those in the spermidine group saw moderate enhancement in memory performance and cognitive ability, The effect was not found in the placebo group.
Source:
Wirth et al. (2018)
How to Use
Take 1 capsule daily with meals in the morning.
Can be taken consistently as part of a daily routine.
Do not exceed the recommended daily dose.
Sustainability
Every decision we make takes the health of our planet into account. At each stage of our operations, we find ways to reduce waste and minimize our carbon footprint.
We source sustainable and environmentally responsible materials and suppliers for our products. Our packaging is 100% biodegradable. And we actively look for ways to improve.
Reuse Tip: Once you’ve taken all your supplements, the tubes can be repurposed to hold paper clips and bobby pins or used in craft projects.
Quality control
Our supplements are vegan, gluten-free, kosher, and halal. They are produced according to the highest standards in the food supplement industry to ensure you receive the best product possible.
International Organization for Standardization
We meet the highest standards in the food supplement industry: ISO 9001 and ISO 2200 qualifications. Learn More
Good Manufacturing Practice
All products are stored in a facility with low humidity and are refrigerated below 25° C to preserve potency. Learn More
Certified Food and Chemical Analysis
The BAV Institut tests every ingredient we use to confirm purity. Learn More
Third-Party Tested
We send all our supplements to third-party certified laboratories for additional quality control.
| Serving size | 1cap |
| Servings per container | 60/120 |
| Spermidine | 3mg |
Ingredients
Mycrocristalline cellulose. HPMC capsule shell 75mg.
How to use
Take 1 capsule daily with meals in the morning. Can be taken consistently as part of a daily routine. Do not exceed the recommended daily dose.
Warnings
Product for use in adults. Food supplements should not be used as a substitute for a balanced diet and healthy lifestyle. This product is not intended to diagnose, treat, or prevent any disease. Do not exceed the recommended daily dose. Keep out of reach of young children.
Allergens
Does not contain: allergens, gluten, dairy, soya, sillicon dioxide.
Spermidine is a type of organic compound called a polyamine. It’s found naturally in foods like wheat and soybeans. As we age, polyamine levels decrease. Multiple health concerns are associated with lower levels of polyamines, but spermidine intake has been linked to delayed aging, a lower risk of death from all causes, and cognitive improvements in older adults at risk for dementia.
Proven Benefits
- Spermidine supplementation has been linked to increased lifespan and improved health span by promoting autophagy, a cellular renewal process.
- Studies suggest spermidine may help improve memory and cognitive performance, potentially offering protection against neurodegenerative diseases like Alzheimer's.
- Spermidine intake has been associated with reduced blood pressure and improved heart function. It may also enhance immune function and reduce inflammation. It may also enhance immune function and reduce inflammation.
Efficacy Studies
- Spermidine delays aging in humans
Results
Spermidine may exert specific effects on multiple organ systems engaged in cardiovascular function, anticancer immune surveillance, and neurodegeneration, thereby reducing the incidence of major age-related diseases.
Source:
Madeo et al. (2018)
Conflicts of interest
All authors are the scientific founders of Samsara Therapeutics. Didac Carmona-Gutierrez and Frank Madeo have equity interest in The Longevity Labs.
2. Higher spermidine intake is linked to lower mortality: a prospective population-based study
Results
All-cause mortality decreased with increased spermidine intake when adjusted for age, sex, and lifestyle factors. Subjects enrolled in the study in 1990 at ages ranging from 45 - 84. They were re-evaluated every 5 years through 2015. Those with the highest levels of spermidine in their diet saw the best health outcomes.
Source:
Kiechl et al. (2018)
3. The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial
Results
Subjects were given nutritional spermidine or a placebo over the course of three months in a double-blind trial. Those in the spermidine group saw moderate enhancement in memory performance and cognitive ability, The effect was not found in the placebo group.
Source:
Wirth et al. (2018)
How to Use
Take 1 capsule daily with meals in the morning.
Can be taken consistently as part of a daily routine.
Do not exceed the recommended daily dose.
Sustainability
Every decision we make takes the health of our planet into account. At each stage of our operations, we find ways to reduce waste and minimize our carbon footprint.
We source sustainable and environmentally responsible materials and suppliers for our products. Our packaging is 100% biodegradable. And we actively look for ways to improve.
Reuse Tip: Once you’ve taken all your supplements, the tubes can be repurposed to hold paper clips and bobby pins or used in craft projects.
Quality control
Our supplements are vegan, gluten-free, kosher, and halal. They are produced according to the highest standards in the food supplement industry to ensure you receive the best product possible.
International Organization for Standardization
We meet the highest standards in the food supplement industry: ISO 9001 and ISO 2200 qualifications. Learn More
Good Manufacturing Practice
All products are stored in a facility with low humidity and are refrigerated below 25° C to preserve potency. Learn More
Certified Food and Chemical Analysis
The BAV Institut tests every ingredient we use to confirm purity. Learn More
Third-Party Tested
We send all our supplements to third-party certified laboratories for additional quality control.
| Serving size | 1cap |
| Servings per container | 60/120 |
| Spermidine | 3mg |
Ingredients
Mycrocristalline cellulose. HPMC capsule shell 75mg.
How to use
Take 1 capsule daily with meals in the morning. Can be taken consistently as part of a daily routine. Do not exceed the recommended daily dose.
Warnings
Product for use in adults. Food supplements should not be used as a substitute for a balanced diet and healthy lifestyle. This product is not intended to diagnose, treat, or prevent any disease. Do not exceed the recommended daily dose. Keep out of reach of young children.
Allergens
Does not contain: allergens, gluten, dairy, soya, sillicon dioxide.
